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ARDA RESEARCH EXPO 2022 : สุดยอดเกษตรไทยยุคใหม่ สุดยอดเกษตรไทยยุคใหม่ ยกระดับด้วยงานวิจัยและนวัตกรรม
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Anti-inflammatory, antioxidant, and anti-apoptotic properties of Thunbergia laurifolia Lindl. aqueous leaf extract on LPS-stimulated RAW 264.7 macrophages. South African Journal of Botany
Abstract Senghoi, W., Konsue. N., Qind. S., Klangbud, W,K, (2024) Anti-inflammatory, antioxidant, and anti-apoptotic properties of Thunbergia laurifolia Lindl. aqueous leaf extract on LPS-stimulated RAW 264.7 macrophages. South African Journal of Botany (Manuscript has been accepted for publication: 25/9/2024) Pecentile 79 https://doi.org/10.7717/peerj.16494
Antioxidant activity, anti-tyrosinase activity, molecular docking studies, and molecular dynamic simulation of active compounds found in nipa palm vinegar
Abstract Tyrosinase is a key enzyme in melanogenesis and its inhibitors have become increasingly because of their potential activity as hypopigmenting agents which have less side effects. Nipa palm vinegar is an aqueous product that is normally used as a food supplement. The aim of this study was to study the determination of antioxidant activity and tyrosinase inhibitory activities of aqueous extract of original nipa palm vinegar (AE O-NPV), nipa palm vinegar powder (NPV-P) and aqueous extract of nipa palm vinegar powder (AE NPV-P) were examined. Nipa palm vinegars were evaluated the phenolic and flavonoid content, and the active compounds
The microbial damage and host response framework: lesson learned from pathogenic survival trajectories and immunoinflammatory responses of Talaromyces marneffei infection
Abstract The adverse outcomes of fungal infection in mammalian hosts depend on the complex interactions between the host immune system and pathogen virulence-associated traits. The main clinical problems arise when the host response is either too weak to effectively eliminate the pathogen or overly aggressive, resulting in host tissue damage rather than protection. This article will highlight current knowledge regarding the virulence attributions and mechanisms involved in the dual-sided role of the host immune system in the immunopathogenesis of the thermally dimorphic fungus Talaromyces marneffei through the lens of the damage response framework (DRF) of microbial pathogenesis model. https://doi.org/10.3389/fimmu.2024.1448729
Adaptation to an amoeba host drives selection of virulence-associated traits and genetic variation in saprotrophic Candida albicans
Abstract Amoebae are micropredators that play an important role in controlling fungal populations in ecosystems. However, the interaction between fungi and their amoebic predators suggests that the pressure from predatory selection can significantly influence the development of fungal virulence and evolutionary processes. Thus, the purpose of this study was to investigate the adaptation of saprotrophic Candida albicans strains during their interactions with Acanthamoeba castellanii. We conducted a comprehensive analysis of survival after co-culture by colony counting of the yeast cells and examining yeast cell phenotypic and genetic characteristics. Our results indicated that exposure to amoebae enhanced the survival capacity of environmental C. albicans and induced