IgG pinpoints culprit bacteria The gut microbiome is thought to play an important role in diseases that are driven by overactivation of the immune system. Gut microbes can cross the gut barrier and activate disease-relevant immune cells, but which gut microbes have this capacity remains difficult to assess. Vujkovic-Cvijin et al. expand on previous studies to present […]
‘The entire protein universe’: AI predicts shape of nearly every known protein DeepMind’s AlphaFold tool has determined the structures of around 200 million proteins. Ewen Callaway The structure of the vitellogenin protein — a precursor of egg yolk — as predicted by the AlphaFold tool.Credit: DeepMind From today, determining the 3D shape of almost
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Long-lasting HIV prevention drug could be game changer — but who will pay? Injectable antiviral cabotegravir provides stronger protection than oral pill, but researchers fear it could be too expensive to make a difference for countries with the greatest disease burden. T.V. Padma Twitter Facebook Email Coloured transmision electron micrograph (TEM) of HIV particles (pink)
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Prolonged contact, especially with a person’s skin lesions, is emerging as the top transmission route. Max Kozlov Monkeypox virus particles (red) infect a cell (blue), as shown in this coloured image from a transmission electron microscope.Credit: NIAID/NIH/SPL As global monkeypox cases continue to soar, researchers are learning more about how the disease is spreading. Early
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One ‘superspreader’ with Omicron shed 1,000 times as much viral RNA as those with Alpha or Delta. A device called the Gesundheit-II can collect viral RNA exhaled by people infected with SARS-CoV-2.Credit: Isabel Teresa Sierra Maldonado People infected with the highly transmissible Alpha, Delta and Omicron variants of SARS-CoV-2 spew out higher amounts of
How much virus does a person with COVID exhale? New research has answers Read More »
Abstract Helicobacter pylori infection causes gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma, and gastric cancer and can also promote thrombosis. It is estimated that approximately 4.5 billion individuals are infected, thus rendering H. pylori the most prevalent microbial pathogen. Currently established regimes for antibiotic treatment are massively challenged by increasing drug resistance and the development of novel
Abstract This study explored the prevalence, genetic diversity, and population structure of azole-resistant Aspergillus fumigatus (ARAf) at Walailak University in Southern Thailand. Three hundred samples were collected from dwellings and workplaces, screened for azole resistance, and tested for drug susceptibility. Molecular detection of alterations in the cyp51A gene and CSP1 typing was performed. Nucleotide polymorphism and haplotype diversity were calculated, and
